Impact of glycemic control on oral health status in type 2 diabetes individuals and its association with salivary and plasma levels of chromogranin A
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- 作者：Evelyn Mikaela Kogawaa ; b ; mikaela.kogawa@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Daniela Corrê ; a Grisib ; dgrisi@terra.com.br" class="auth_mail" title="E-mail the corresponding author ; Denise Pinheiro Falcã ; oa ; dfalcao@terra.com.br" class="auth_mail" title="E-mail the corresponding author ; Ingrid Aquino Amorimc ; d ; ingridaquinos2@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Taia Maria Berto Rezendeb ; c ; d ; taiambr@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Izabel Cristina Rodrigues da Silvae ; belbiomedica@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Osmar Nascimento Silvaf ; osmar.silva@catolica.edu.br" class="auth_mail" title="E-mail the corresponding author ; Octá ; vio Luiz Francod ; g ; h ; ocfranco@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Rivadá ; vio Fernandes Batista de Amorima ; rivadavioamorim@hotmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：DM ; diabetes mellitus ; T2DM ; type 2 diabetes mellitus ; CHGA ; chromogranin A ; DMFT ; decayed ; missed and filled teeth ; FPG ; fasting plasma glucose ; HbA1c ; glycated hemoglobin ; BMI ; body mass index ; SWS ; stimulated whole saliva ; PI ; plaque index ; CAL ; clinical attachment loss ; PD ; probing depth ; BOP ; bleeding on probing ; ICCs ; intraclass correlation coefficients ; HPA ; hypothalamus&ndash ; pituitary&ndash ; adrenal ; ANS ; autonomous nervous system ; PST ; pancreastatin ; AGEs ; advanced glycation end product
- 刊名：Archives of Oral Biology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：62
- 期：Complete
- 页码：10-19
- 全文大小：677 K
文摘
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It is the first time that CHGA is associated with oral health status in T2DM patients.
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Clinical attachment loss was more prevalent in T2DM groups and worst in poorly controlled T2DM patients.
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Higher plasma and salivary CHGA levels were found in type 2 diabetes patients.
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High salivary CHGA levels were associated with worst periodontal parameters.