Metastatic tumors to the oral cavity are uncommon. In this article, we report a case of metastatic adenocarcinoma of the colon to the mandible with imaging features. A 73-year-old man with a history of colon cancer and liver metastasis was referred to our hospital with a chief complaint of swelling and pain in the right mandible. Panoramic radiograph revealed a radiolucency with ill-defined margin. Computed tomography showed an osteolytic lesion with cortical bone destruction. Magnetic resonance imaging showed a round-shaped homogeneous intensity mass expanding from the mandible. Histopathological diagnosis revealed metastatic adenocarcinoma of the colon.