The role of IL18-607C > A and IL18-137G > C promoter polymorphisms in antidepressant treatment phenotypes: A preliminary report
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- 作者：Marlene Santosa ; b ; c ; mmarlenes@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Serafim Carvalhod ; e ; Luí ; s Limab ; f ; Jorge Mota-Pereirag ; Paulo Pimentelh ; Dulce Maiah ; Diana Correiad ; Sofia Gomesd ; Agostinho Cruzb ; Rui Medeirosa ; i ; j ; k ; ruimedei@ipoporto.min-saude.pt" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cytokines ; Antidepressants ; IL18 ; Relapse ; Genetic polymorphisms
- 刊名：Neuroscience Letters
- 出版年：2016
- 出版时间：27 May 2016
- 年：2016
- 卷：622
- 期：Complete
- 页码：107-112
- 全文大小：588 K
文摘
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IL18-607C > A and IL18-137G > C polymorphisms were associated with the risk of depression relapse.
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IL18 peripheral mRNA levels were found upregulated in IL18-607 CA/AA carriers.
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No association was found between SNPs and the development of TRD.