Fine structure of interleukin 18 (IL-18) receptor-immunoreactive neurons in the retrosplenial cortex and its changes in IL18 knockout mice

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• 作者：Tetsu Hayakawa^a ; ^{tetsu@hyo-med.ac.jp} ; Masaki Hata^a ; Sachi Kuwahara-Otani^b ; Kyosuke Yamanishi^c ; Hideshi Yagi^b ; Haruki Okamura^a
• 关键词：Immunohistochemistry ; Cytokines ; Ultrastructure ; Degeneration ; Granular retrosplenial cortex
• 刊名：Journal of Chemical Neuroanatomy
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：78
• 期：Complete
• 页码：96-101
• 全文大小：1977 K
• 卷排序：78

文摘

IL-18R-ir neurons are located in the layer V of granular RSC. IL-18R-ir neurons are medium-sized neurons with little cytoplasm. No IL-18R-ir neurons are found in the RSC of the IL-18 knockout mouse. Presumed IL-18R-ir neurons in the RSC degenerate in the IL-18 knockout mouse.