IL-23-dependent Blimp-1 enhances Th17 pathogenic factors including GM-CSF and IFN-γ
Distal Lck-Cre-mediated Blimp-1 deletion in peripheral T cells ameliorates EAE
Blimp-1 co-localizes with RORγt and STAT-3 at Il23r, Il17a, and Csf2 enhancer sites
Blimp-1 also represses Il2 and Bcl6, which destabilize the Th17 inflammatory program