Interleukin-15-mediated inflammation promotes non-alcoholic fatty liver disease
详细信息 查看全文
- 作者：Yuneivy Cepero-Donatesa ; Gré ; gory Lacraza ; b ; Farnaz Ghobadia ; Volatiana Rakotoariveloa ; Sakina Orkhisa ; Marian Mayhuea ; Yi-Guang Chenc ; Marek Rola-Pleszczynskia ; e ; Alfredo Menendezd ; e ; Subburaj Ilangumarana ; e ; Sheela Ramanathana ; e ; Sheela.Ramanathan@Usherbrooke.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：NAFLD ; non-alcoholic fatty liver disease ; IHL ; intrahepatic lymphocytes ; NASH ; non-alcoholic steatohepatitis ; PPAR ; peroxisome proliferator-activated receptor ; ER ; endoplasmic reticulum
- 刊名：Cytokine
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：82
- 期：Complete
- 页码：102-111
- 全文大小：3092 K
文摘
- •
Absence of IL-15 or IL-15Rα protects from NAFLD.
- •
Production of chemokines is decreased in the absence of IL-15 or IL-15Rα.
- •
In NAFLD, CD4+, CD8+, NK and NKT cells are increased in numbers in the liver.