Triterpenoid saponins with anti-inflammatory activities from Ilex pubescens roots

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• 作者：Peng Wu^a ; Hui Gao^a ; Jian-Xin Liu^b ; Liang Liu^b ; Hua Zhou^b ; ^{hzhou@must.edu.mo} ; Zhong-Qiu Liu^a ; ^b ; ^{liuzq@gzucm.edu.cn}
• 关键词：Ilex pubescens ; Aquifoliaceae ; Triterpenoid saponins ; RAW 264.7 macrophages ; Anti-inflammatory
• 刊名：Phytochemistry
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：134
• 期：Complete
• 页码：122-132
• 全文大小：1404 K
• 卷排序：134

文摘

Nineteen triterpene saponins were isolated from the roots of Ilex pubescens. Structures were elucidated by spectroscopic analysis. Twenty seven compounds were evaluated for anti-inflammatory activity. Two compounds had potent anti-inflammatory effects.