Comparative innate immune interactions of human and bovine secretory IgA with pathogenic and non-pathogenic bacteria

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• 作者：Alison J. Hodgkinson^a ; ^{ali.hodgkinson@agresearch.co.nz} ; Julie Cakebread^a ; Megan Callaghan^a ; Paul Harris^a ; Rachel Brunt^a ; Rachel C. Anderson^b ; ^c ; Kelly M. Armstrong^b ; Brendan Haigh^a
• 关键词：Secretory IgA ; Bovine IgA ; Human IgA ; Bacteria ; Bacteria binding
• 刊名：Developmental & Comparative Immunology
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：68
• 期：Complete
• 页码：21-25
• 全文大小：606 K
• 卷排序：68

文摘

Milk-derived SIgA has innate-immune interactions with bacteria. Percentages of different bacteria bound by human and bovine SIgA varied from 30 to 90%. Human and bovine SIgA interacted with bacteria in a comparable way.