Successful Therapy With Rituximab of Refractory Acute Humoral Renal Transplant Rejection: A Case Report
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- 作者：A. Celik ; F. Saglam ; C. Cavdar ; A. Sifil ; K. Atila ; S. Sarioglu ; S. Bora ; H. Gulay ; T. Camsari
- 关键词：Cardiac transplantation ; Toxoplasmosis ; Diagnosis ; Prophylaxis
- 刊名：Transplantation Proceedings
- 出版年：2008
- 出版时间：January-February 2008
- 年：2008
- 卷：40
- 期：1
- 页码：302-304
- 全文大小：236 K
文摘
Acute humoral rejection (AHR) is generally less responsive to conventional anti-rejection treatment with consequent allograft losses. Therapeutic options include antilymphocyte antibody (ATG), intravenous immunglobulin (IVIG), plasmapheresis, or immunoadsorption with protein A together with intensification of immunsuppression with a tacrolimus/mycophenolate mofetil combination. This report describes a transplant recipient who responded to rituximab therapy as treatment for steroid-, ATG-, IVIG-, and plasmapheresis-resistant AHR.