A shrimp pacifastin light chain-like inhibitor: Molecular identification and role in the control of the prophenoloxidase system
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- 作者：Pakkakul Sangsuriyaa ; b ; Walaiporn Charoensapsrib ; c ; Sudarat Chomwonga ; d ; Saengchan Senapinb ; c ; Anchalee Tassanakajona ; Piti Amparyupa ; b ; piti.amp@biotec.or.th" class="auth_mail" title="E-mail the corresponding author
- 关键词：Shrimp immunity ; Penaeus monodon ; Serine proteinase inhibitor ; Melanization ; Prophenoloxidase ; Pacifastin ; Kunitz
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：January 2016
- 年：2016
- 卷：54
- 期：1
- 页码：32-45
- 全文大小：3224 K
文摘
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PmPacifastin-like gene was identified from a SSH library of PmproPO1/2 knockdown shrimp.
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PmPacifastin-like protein contains both pacifastin light chain- and kunitz-domains.
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Suppression of PmPacifastin-like gene significantly increased shrimp PO activity.
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PmPacifastin-like gene implicates in the negative regulation of the shrimp proPO system.