Preferential combination between the light and heavy chain isotypes of fish immunoglobulins
详细信息 查看全文
- 作者：Nu Zhanga ; b ; Xu-Jie Zhanga ; c ; Yu-Long Songa ; b ; Xiao-Bing Lua ; b ; Dan-Dan Chena ; Xiao-Qin Xiaa ; J. Oriol Sunyerd ; Yong-An Zhanga ; yzhang@ihb.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Light chain subisotype ; Heavy chain ; IgM ; IgT ; Preferential combination ; Rainbow trout
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：61
- 期：Complete
- 页码：169-179
- 全文大小：2779 K
文摘
- •
Eight subisotypes belonging to 4 IgL isotypes (IgLκF, IgLκG, IgLσ, and IgLλ) were identified from rainbow trout.
- •
The genomic organizations of trout IgL isotypes were characterized.
- •
Trout IgL isotypes participated in immune responses to stimulants.
- •
Trout IgLκG and IgLσ isotypes preferentially bonded with the heavy chains of IgM and IgT, respectively.