The variegated aspects of Immunoglobulin A
详细信息 查看全文
- 作者：Elena Zagatoa ; Elisa Mazzinia ; Maria Rescignoa ; b ; maria.rescigno@ieo.eu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Immunoglobulin A ; Microbiota ; Genetic background
- 刊名：Immunology Letters
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：178
- 期：Complete
- 页码：45-49
- 全文大小：530 K
文摘
- •
F1 BALB/c x C57BL/6 mixed background has intermediate amount of both fecal and serum IgAs.
- •
Innate IgAs reacting towards commensal bacteria promote de novo differentiation of antigen-specific responses.
- •
Commensal bacteria induce only a mucosal IgA response, without systemic IgG.