Potential role for mucosal IgA in modulating Haemonchus contortus adult worm infection in sheep
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- 作者：J.N. Herná ; ndeza ; A. Herná ; ndeza ; M.J. Stearb ; M. Conde-Felipea ; E. Rodrí ; gueza ; D. Piedrafitac ; 1 ; J.F. Gonzá ; leza ; 1 ; jorgefrancisco.gonzalez@ulpgc.es" class="auth_mail" title="E-mail the corresponding author
- 关键词：Immunoglobulin-A ; Haemonchus contortus ; Sheep-nematoda ; Worm-length ; Canaria Hair Breed ; Canaria Sheep
- 刊名：Veterinary Parasitology
- 出版年：2016
- 出版时间：15 June 2016
- 年：2016
- 卷：223
- 期：Complete
- 页码：153-158
- 全文大小：875 K
文摘
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The Canaria Hair Breed (CHB) sheep is a resistant breed which targets the adult Haemonchus contortus parasitic stage.
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Negative correlations between mucosal IgA and adult worms were only detected in CHB sheep not in the susceptible Canaria sheep (CS).
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Conversely, a negative correlation between mIgA and larvae was only detected in susceptible CS.
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Mucosal IgA may play a differential role in parasite modulation of larval and adult stages in CHB sheep and CS.