Transcriptional Control of Synaptic Remodeling through Regulated Expression of an Immunoglobulin Superfamily Protein
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- 作者：Siwei He1 ; 5 ; Alison Philbrook3 ; 5 ; Rebecca McWhirter2 ; Christopher V. Gabel4 ; Daniel G. Taub4 ; Maximilian H. Carter2 ; Isabella M. Hanna2 ; Michael M. Francis3 ; michael.francis@umassmed.edu" class="auth_mail" title="E-mail the corresponding author ; David M. Miller III1 ; 2 ; david.miller@vanderbilt.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Current Biology
- 出版年：2015
- 出版时间：5 October 2015
- 年：2015
- 卷：25
- 期：19
- 页码：2541-2548
- 全文大小：2689 K
文摘
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The IgSF protein OIG-1 antagonizes synaptic remodeling
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OIG-1 blocks the relocation of ACh receptors to new synapses
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IRX-1 downregulates OIG-1 to unleash the remodeling program