Cutting through Complexity: The Proteolytic Properties of Alternate Immunoproteasome Complexes

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• 作者：Ciyu Yang¹ ; Marion Schmidt¹ ; ^{marion.schmidt@einstein.yu.edu" class="auth_mail}
• 刊名：Chemistry & Biology
• 出版年：24 April 2014
• 年：2014
• 卷：21
• 期：4
• 页码：435-436
• 全文大小：96 K

文摘

The proteasome core interacts with different activators and incorporates alternate active subunits, thereby generating a diverse pool of subspecies. The enzymatic properties of these different species are not well understood. In this issue of Chemistry & Biology, Raule and colleagues present a comprehensive enzymatic characterization of immunoproteasome complexes associated with the proteasome activator PA28.