Stomatin-like protein 2 of turbot Scopthalmus maximus: Gene cloning, expression profiling and immunoregulatory properties
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- 作者：Heng Chia ; b ; Yong-hua Hua ; b ; huyonghua@qdio.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Stomatin like protein 2 ; Scopthalmus maximus ; Gene cloning ; Immunoregulation
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：49
- 期：Complete
- 页码：436-441
- 全文大小：2142 K
文摘
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A SLP-2 (SmSLP-2) gene in turbot (Scopthalmus maximus) was identified.
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Both viral and bacterial pathogen infection resulted in up-regulation of SmSLP-2 mRNA in head kidney and spleen.
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The major pool of SmSLP-2 is the peripheral membrane in ZF4 cells.
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SmSLP-2 modulates IL-2 expression via active NFκB signaling pathway.