Quantitative, single-step dual measurement of hemoglobin A1c and total hemoglobin in human whole blood using a gold sandwich immunochromatographic assay for personalized medicine
详细信息 查看全文
- 作者：Shu Hwang Anga ; Musalman Rambelia ; T. Malathi Thevarajahb ; Yatimah Binti Aliasa ; Sook Mei Khora ; naomikhor@um.edu.my" class="auth_mail" title="E-mail the corresponding author
- 关键词：Type 2 Diabetes Mellitus ; Hemoglobin A1c ; Total hemoglobin ; Lateral flow immunosensor ; Colloidal gold-based immunochromatographic assay ; Single-step dual measurement
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 April 2016
- 年：2016
- 卷：78
- 期：Complete
- 页码：187-193
- 全文大小：676 K
文摘
- •
Sandwich immunosensor developed to measure HbA1c and total hemoglobin quantitatively.
- •
Determining the ratio of HbA1c to total hemoglobin was performed in a single step.
- •
Distinguishing blood samples with elevated HbF from normal samples was demonstrated.
- •
Evaluation of whole blood samples showed excellent selectivity and analytical consistency.