Impact of vaccination on invasive pneumococcal disease in adults with focus on the immunosuppressed
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- 作者：Anna Sangila ; b ; asangilbetriu@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Mariona Xercavinsc ; Mò ; nica Rodrí ; guez-Carballeiraa ; Marta André ; sd ; Montse Rieraa ; Elena Espejod ; Josefa Pé ; rezc ; Javier Garaua ; Esther Calboa ; b
- 关键词：Invasive pneumococcal disease ; Streptococcus pneumoniae ; Serotypes ; Pneumococcal conjugate vaccines ; Immunosuppressed
- 刊名：Journal of Infection
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：71
- 期：4
- 页码：422-427
- 全文大小：1078 K
文摘
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IPD incidence significantly declined by 60% over the study period.
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A parallel decrease in the proportion of IPD isolates included in PCV7 and PCV13 vaccines was observed.
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Global vaccine coverage was for PCV7 21.6% vs. 28.8% in general and in the ISP and for PCV13, 64.5% and 56.6%, respectively.
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Penicillin resistance experienced a significant decline. No changes in mortality were detected.
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Coverage of PCV13 vaccine might be suboptimal for immunosuppressed population in the coming years.