A 13-year survey of pneumococcal nasopharyngeal carriage in children with acute otitis media following PCV7 and PCV13 implementation
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- 作者：Robert Cohena ; b ; c ; d ; e ; Emmanuelle Varonf ; Catherine Doitg ; h ; Catherine Schlemmerb ; Olivier Romainb ; Franck Thollotb ; d ; Sté ; phane Bé ; chetb ; Sté ; phane Bonacorsig ; h ; Corinne Levya ; b ; c ; d ; corinne.levy@activ-france.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Pneumococcal nasopharyngeal carriage ; Children ; Acute otitis media ; PCV7 and PCV13 impact
- 刊名：Vaccine
- 出版年：2015
- 出版时间：22 September 2015
- 年：2015
- 卷：33
- 期：39
- 页码：5118-5126
- 全文大小：1572 K
文摘
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During 13 years, Sp carriage was assessed annually for patients (>7900) with AOM.
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Before PCV7 period, PCV7 serotypes accounted for 45% and now they have disappeared.
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ST 19A increased from 9 to 16% before PCV13 implementation and decreased to 1% after.
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Predominant serotypes after PCV13 implementation were 15B/C, 11A, 15A, and 35B.
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Penicillin non-susceptible Sp decreased from 67% to 33% over 13 years.