Impact of PCV7/PCV13 introduction on invasive pneumococcal disease (IPD) in young children: Comparison between meningitis and non-meningitis IPD
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- 作者：S. Ben-Shimola ; b ; D. Greenberga ; b ; N. Givon-Lavia ; b ; Y. Schlesingerc ; D. Mirond ; S. Avinere ; R. Daganb ; rdagan@bgu.ac.il" class="auth_mail" title="E-mail the corresponding author ; On behalf of the Israel Bacteremia ; Meningitis Active Surveillance Group
- 关键词：PCV7 ; PCV13 ; IPD ; Children ; Meningitis ; Impact
- 刊名：Vaccine
- 出版年：2016
- 出版时间：31 August 2016
- 年：2016
- 卷：34
- 期：38
- 页码：4543-4550
- 全文大小：831 K
文摘
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We compared PCV7/13 impact on pneumococcal-meningitis vs. other IPD in children <5 y.
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Meningitis patients were younger and had higher proportion of non-PCV13 serotypes.
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Meningitis rates in children <5 y decreased by 27%, while other IPD decreased by 69%.
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Rates of both meningitis and other IPD caused by PCV13 serotypes declined by >90%.
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Non-PCV13 serotypes increased in meningitis relatively to other IPD.