Living Kidney Donors With Adrenal Incidentalomas: Are They Appropriate Donors?

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• 作者：Emre Arpali^a ; ^{arpali@surgery.wisc.edu" class="auth_mail" title="E-mail the corresponding author} ; Atilla Aslan^b ; Joseph Scalea^c ; Cihan Karatas^a ; Serkan Akinci^d ; Mert Altinel^e ; Burak Kocak^a
• 刊名：Urology
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：87
• 期：Complete
• 页码：100-105
• 全文大小：249 K

文摘

To determine the incidence of adrenal incidentalomas (AIs) in a single-center series of living renal donors, to describe an evaluation algorithm for AIs in this patient population, and to compare the complication rates of hand-assisted laparoscopic donor nephrectomy (HALDN) with those of combined HALDN and adrenalectomy.

Methods

We performed a single-center, retrospective study of consecutive living kidney donors who underwent laparoscopic nephrectomy for transplantation, with or without simultaneous ipsilateral adrenalectomy, between January 2008 and September 2014.

Results

During the study period, AIs were detected in 18 of 1033 potential living renal donors who underwent computerized tomographic angiography. Application of additional donor selection criteria and of an adrenal mass assessment algorithm resulted in 849 HALDN, of which 13 were combined with simultaneous adrenalectomy. The hospital length of stay (2.4 vs 2.6 days), perioperative (0.025 vs 0.077), early (0.073 vs 0.077), and late (0.014 vs 0.077) postoperative complication rates, and conversion to open donor nephrectomy (0.008 vs 0.00) were not significantly different. Mean operative time was significantly longer in the adrenalectomy group. None of the adrenal masses were malignant.

Conclusion

Here, we presented our algorithm to manage the living kidney donors with AIs. Although donor population with AIs was relatively small in number, simultaneous adrenalectomy and ipsilateral nephrectomy seemed to be technically safe and conferred no identifiable increased risk of malignancy for the kidney transplant donor, when the incidentaloma is nonfunctional and less than or equal to 4 cm as assessed by preoperative imaging.