Increased functional connectivity one week after motor learning and tDCS in stroke patients

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• 作者：Sté ; phanie Lefebvre^a ; ^b ; Laurence Dricot^a ; Patrice Laloux^a ; ^b ; Philippe Desfontaines^c ; Fré ; dé ; ric Evrard^d ; André ; Peeters^e ; Jacques Jamart^f ; Yves Vandermeeren^a ; ^b ; ^g ; ^{yves.vandermeeren@uclouvain.be}
• 关键词：ANOVA ; analysis of variance ; damH ; damaged hemisphere ; DAN ; dorsal attentional network ; FC ; functional connectivity ; ICA ; Independent Component Analysis ; LI ; Learning Index ; M1 ; primary motor cortex ; NIBS ; non-invasive brain stimulation ; PI ; performance index ; PMd ; dorsal premotor cortex ; qFDR ; q False Discovery Rate ; ROI ; region of interest ; rs-fMRI ; resting-state functional magnetic resonance imaging ; SAT ; speed/accuracy trade-off ; SMA ; supplementary motor area ; SMN ; somatomotor network ; tDCS
• 刊名：Neuroscience
• 出版年：2017
• 出版时间：6 January 2017
• 年：2017
• 卷：340
• 期：Complete
• 页码：424-435
• 全文大小：2201 K
• 卷排序：340

文摘

Dual-tDCS enhanced motor skill learning and retention in chronic stroke patients (80/85). Dual-tDCS + motor learning increased FC in ipsilesional (pre-)motor cortex @ 1 week (84/85). Both seed and ICA-based analyses showed a FC reorganization following dual-tDCS (80/85). The observed changes of FC lasting well beyond what previously reported after tDCS (83/85). This study promotes tDCS use as efficient add-on intervention in neurorehabilitation (84/85).