N-Heterocyclic carbene-catalyzed hydroacylation of isatins with aldehydes: access to 3-acyloxy-1,3-dihydro-2H-indol-2-ones

详细信息    查看全文

• 作者：Ding  ; Du^a ;   ; ^{ddmn9999@cpu.edu.cn} ; Yingyan  ; Lu^a ; Jianlin  ; Jin^a ; Weifang  ; Tang^a ; Tao  ; Lu^a ;   ; ^b ;   ; ^{lut163@163.com}
• 关键词：N-Heterocyclic carbenes ; Organocatalysis ; Hydroacylation ; Isatins ; Aldehydes
• 刊名：Tetrahedron
• 出版年：2011
• 出版时间：30 September 2011
• 年：2011
• 卷：67
• 期：39
• 页码：7557-7562
• 全文大小：636 K

文摘

The N-heterocyclic carbene-catalyzed hydroacylation of isatins with aldehydes has been described. This process offers a highly efficient and atom-ecomonical access to 3-acyloxy-1,3-dihydro-2H-indol-2-ones in good to excellent yields.