Synthesis of dibenzo[d,f]diazepinones and alkenylindolinones through ring transformation of 2H-pyran-2-one-3-carbonitriles by indolin-2-ones

详细信息    查看全文

• 作者：Sandeep Kumar^a ; Ramendra Pratap^b ; Abhinav Kumar^a ; Brijesh Kumar^c ; Vishnu K. Tandon^a ; Vishnu Ji Ram^a ; ^{vjiram@yahoo.com}
• 关键词：Dibenzo[d ; f][1 ; 3]diazepine ; Alkenylindolin-2-one ; 2H-Pyran-2-one ; Indolin-2-one ; Ring transformation
• 刊名：Tetrahedron
• 出版年：2013
• 出版时间：17 June, 2013
• 年：2013
• 卷：69
• 期：24
• 页码：4857-4865
• 全文大小：980 K

文摘

First ever synthesis of functionalized 5,7-dihydro-6H-dibenzo[d,f][1,3]diazepin-6-ones (6, 9) has been developed through base induced ring transformation of 2H-pyran-2-one-3-carbonitriles with indolin-2-ones. A protocol for alkenylating indolin-2-ones by 2H-pyran-2-one-3-carbonitriles has also been developed to obtain 3-alkenylindolin-2-ones (11). The nature and behaviour of intermolecular interactions of these compounds are studied by single crystal-X-ray analysis and quantum chemical calculations.