A novel multiplex poliovirus binding inhibition assay applicable for large serosurveillance and vaccine studies, without the use of live poliovirus

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• 作者：Rutger M. Schepp^a ; ^{Rutger.Schepp@rivm.nl} ; Guy A.M. Berbers^a ; José ; A. Ferreira^b ; Johan H. Reimerink^a ; Fiona R. van der Klis^a
• 关键词：Polio eradication ; Immunoassay ; Poliovirus ; Neutralization test ; Multiplex ; Binding inhibition
• 刊名：Journal of Virological Methods
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：241
• 期：Complete
• 页码：15-23
• 全文大小：1203 K
• 卷排序：241

文摘

Simultaneous quantification of serum antibodies directed to all three poliovirus types. Use of Inactivated poliovirus increases biosafety. High throughput and low volume of serum are needed.