In vivo digestomics of milk proteins in human milk and infant formula using a suckling rat pup model

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• 作者：Yasuaki Wada^a ; ^b ; Brett S. Phinney^c ; Darren Weber^c ; Bo Lö ; nnerdal^a ; ^{bllonnerdal@ucdavis.edu}
• 关键词：ACE ; angiotensin I-converting enzyme ; AH ; antihypertensive ; α-LA ; α-lactalbumin ; AO ; antioxidative ; CN ; casein ; DPP4i ; dipeptidyl peptidase-IV inhibitory ; HM ; human milk ; IF ; infant formula ; LC&ndash ; MS/MS ; liquid chromatography conjugated with tandem mass spectrometry ; LF ; lactoferrin ; OP ; opioid ; OPN ; osteopontin ; PEPi ; prolyl endopeptidase-inhibitory ; WP ; whey protein
• 刊名：Peptides
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：88
• 期：Complete
• 页码：18-31
• 全文大小：2084 K
• 卷排序：88

文摘

Suckling rat pups were intubated with human milk or infant formula, and milk protein-derived peptides formed in the intestine were analyzed. Release of peptides was concentrated to specific regions, suggesting their resistance to gastro intestinal digestion. Some of the bioactive peptides are likely of biological significance in neonatal health and development.