Potential mechanisms underlying ectodermal differentiation of Wharton's jelly mesenchymal stem cells
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- 作者：Sushma Jadalannagaria ; b ; Abigale M. Berrya ; Richard A. Hopkinsc ; Dhaval Bhavsard ; Omar S. Aljitawia ; b ; omar_aljitawi@urmc.Rochester.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Wharton's jelly mesenchymal stem cells ; Decellularized Wharton's jelly matrix ; Osteogenic differentiation media ; Ectodermal differentiation ; Hair-like structures ; Beta-catenin
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：16 September 2016
- 年：2016
- 卷：478
- 期：2
- 页码：831-837
- 全文大小：2657 K
文摘
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WJMSCs on DWJM in OD generate hair-like structures.
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CK-19, αSMA positive cells suggest potential epithelial-mesenchymal interactions.
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β-Catenin, noggin, TGF-b & SMAD play an important role in ectodermal differentiation.