Increased complement C4d deposition at the maternal-fetal interface in unexplained recurrent miscarriage
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- 作者：Tess Meulemana ; b ; t.meuleman@lumc.nl" class="auth_mail" title="E-mail the corresponding author ; Danielle Cohenc ; Godelieve M.J.S. Swingsb ; Kimberly Veraarc ; Frans H.J. Claasb ; Kitty W.M. Bloemenkampa
- 关键词：LUMC ; Leiden University Medical Centre ; LMWH ; low molecular weight heparin ; IUGR ; intra-uterine growth restriction ; HELLP ; hemolysis elevated liver enzymes and low platelets ; IQR ; interquartile range ; SLE ; systemic lupus erythematosus ; MCP ; membrane cofactor protein
- 刊名：Journal of Reproductive Immunology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：113
- 期：Complete
- 页码：54-60
- 全文大小：1453 K
文摘
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C4d is increased on trophoblast tissue in unexplained recurrent miscarriage.
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Increase of C4d may reflect anti-fetal immunity in women with recurrent miscarriage.
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Knowledge of this pathogenic mechanism may lead to new treatment strategies.