Viability and functional recovery of pancreatic islet cells co-cultured with liver, salivary glands and intestine cells

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• 作者：Durdi Qujeq ; Ph.D^a ; ^b ; ^{d.qujeq@mubabol.ac.ir} ; ^{dqujeq@gmail.com} (Prof.) ; Zeinab Abedian^a
• 关键词：Pancreatic islet cells ; Liver ; Insulin release ; Intestine ; Salivary gland ; Signaling factors
• 刊名：Process Biochemistry
• 出版年：2016
• 出版时间：December 2016
• 年：2016
• 卷：51
• 期：12
• 页码：2155-2161
• 全文大小：1112 K
• 卷排序：51

文摘

Isolation of rat primary salivary gland, liver and intestinal cells were carried out. Islets co-cultured with rat primary salivary gland, liver and intestinal cells. Rats received co-cultured islets with primary salivary gland, liver and intestinal cells. Islet cells co-cultured with liver, salivary glands and intestine cells facilitate the injured islet to recover its function. This study demonstrated that co-culturing strategy is a novel method for the survival and improvement of islets.