Transforming growth factor β (CiTGF-β) gene expression is induced in the inflammatory reaction of Ciona intestinalis
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- 作者：Aiti Vizzini ; Felicia Di Falco ; Daniela Parrinello ; Maria Antonietta Sanfratello ; Matteo Cammarata ; matteo.cammarata@unipa.it" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ascidian ; Transforming growth factor ; TGF ; Hemocyte ; Inflammation ; LPS ; Ciona intestinalis
- 刊名：Developmental & Comparative Immunology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：55
- 期：Complete
- 页码：102-110
- 全文大小：3019 K
文摘
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A gene of the transforming grow factor are transcribed in Ciona intestinalis.
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The phylogenetic tree revealed that the CiTGF-β is related to mammalian TGF.
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Sequence analysis and structure showed that CiTGF-β share a common ancestor in the chordate lineages.
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The CiTGF-β mRNA were expressed in the vessels hemocytes of the pharynx.
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Real time -PCR analyses revealed that CiTGF-β mRNA expression was upregulated by LPS challenge.