Separation of extra- and intracellular metabolites using hyperpolarized 13C diffusion weighted MR
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- 作者：Bertram L. Koelscha ; b ; Renuka Srirama ; renuka.sriram@ucsf.edu" class="auth_mail" title="E-mail the corresponding author ; Kayvan R. Kesharic ; d ; Christine Leon Swishera ; b ; Mark Van Criekingea ; Subramaniam Sukumara ; Daniel B. Vignerona ; b ; Zhen J. Wanga ; Peder E.Z. Larsona ; b ; John Kurhanewicza ; b
- 关键词：ADC ; apparent diffusion coefficient ; MR ; magnetic resonance ; MRS ; magnetic resonance spectroscopy ; DNP ; dynamic nuclear polarization ; RCC ; renal cell carcinoma ; DMEM ; Dulbeco&rsquo ; s Modified Eagle&rsquo ; s medium ; DIDS ; 4 ; 4&prime ; -Diisothiocyanostilbene-2 ; 2&prime ; -disulfonic acid ; MCT ; monocarboxylate transporter ; LDH ; lactate dehydrogenase ; TCA ; tricarboxylic acid ; Lintra ; intracellular lactate ; Lextra ; extracellular lactate ; Ltotal ; total lactate ; Pintra ; intracellular pyruvate ; Pextra ; extrac
- 刊名：Journal of Magnetic Resonance
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：270
- 期：Complete
- 页码：115-123
- 全文大小：717 K
文摘
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Intra- and extracellular differentiation by hyperpolarized diffusion weighted 13C MR.
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Measurement of intracellular ADC using hyperpolarized 13C NMR.
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Real-time detection of the membrane transport of hyperpolarized lactate and pyruvate.