Synthesis of two trisaccharides related to the hepatoprotective phenylethanoids leonoside E and F isolated from Leonurus japonicus Houtt
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- 作者：Darshita Budhadev ; Balaram Mukhopadhyay
- 关键词：Glycosylation ; La(OTf)3 ; Phenylethanoid glycosides
- 刊名：Carbohydrate Research
- 出版年：30 January, 2014
- 年：2014
- 卷：384
- 期：Complete
- 页码：51-55
- 全文大小：606 K
文摘
The chemical synthesis of two trisaccharides related to leonoside E and F is reported. The target oligosaccharides were prepared in the form of their p-methoxyphenyl glycosides using a common disaccharide acceptor. All reaction steps were high yielding (>80%) and the stereoselective glycosylations were achieved by activation of the thioglycoside donors using N-iodosuccinimide in the presence of La(OTf)3.