36 patients(32 females and 4 males) were included, the mean age was 35.2 ± 17.3 years, all patients were non-smokers and non-obese. All patients were subjected to routine investigations, Echocardiography, CT pulmonary angiography and full night polysomnography. All cases pulmonary hypertension related to cardiac disease or collagenic vascular disease or Thromboembolic disease were excluded.
The mean AHI was 13.8 ± 8.3/h of sleep with OSA proved in 5 patients (13.9%) and CSR/CSA proved in 2 patients (5.56%). Nocturnal desaturation was more pronounced in the studied patient as 27 patients (75%) showed nocturnal desaturation. There was a significant correlation between SDB measures and baseline oxygen saturation, lowest oxygen saturation during walking and mean PAP.
SDB is significant in patients with IPAH and can affect the disease progression and the quality of life of those patients. All patients should undergo sleep study to identify patients who are in need of nocturnal oxygen therapy or in need for CPAP therapy in case of OSA.