Synthesis, molecular structure, quantum mechanical studies and urease inhibition assay of two new isatin derived sulfonylhydrazides

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• 作者：Muhammad Arshad^a ; Mehwish Jadoon^b ; Zafar Iqbal^b ; Mehwish Fatima^a ; Muhammad Ali^b ; Khurshid Ayub^b ; Ashfaq Mahmood Qureshi^c ; Muhammad Ashraf^d ; Muhammad Nadeem Arshad^e ; ^f ; Abdullah M. Asiri^e ; ^f ; Amir Waseem^g ; Tariq Mahmood^b ; ^{mahmood@ciit.net.pk}
• 关键词：Isatin ; X-ray ; DFT ; Enzyme inhibition
• 刊名：Journal of Molecular Structure
• 出版年：2017
• 出版时间：5 April 2017
• 年：2017
• 卷：1133
• 期：Complete
• 页码：80-89
• 全文大小：1452 K
• 卷排序：1133

文摘

Synthesis of two new isatin derived sulfonyl hydrazides was performed. The spectroanalytical theoretical results strongly agree with experiment. Enzyme inhibition potential was tested in vitro against Bacillus pasteurii urease.