PPARα activation drives demethylation of the CpG islands of the Gadd45b promoter in the mouse liver
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- 作者：Jung-Hwan Kima ; junghwan.kim@gnu.ac.kr" class="auth_mail" title="E-mail the corresponding author ; Lilik Duwi Wahyudia ; Kee K. Kimb ; Frank J. Gonzalezc
- 关键词：Gadd45b ; PPARα ; CpG methylation
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：5 August 2016
- 年：2016
- 卷：476
- 期：4
- 页码：293-298
- 全文大小：1358 K
文摘
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Epigenetic modification of Gadd45b promoter is proposed.
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Gadd45b mRNA is regulated through CpG methylation.
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Demethylations of the CpG islands are triggered by PPARα activation.