Benzyl ITC suppressed LPS-triggered COX pathway activation in human PBMC.
Benzyl nitrile did not influence PGE2 synthesis.
Benzyl ITC blocked leukotriene LTB4 release in human PBMC.
Benzyl ITC mediated inhibition of ERK1/2 and c-Jun preceded COX-2 suppression.
Benzyl ITC reduced the activation and function of activated T lymphocytes.