Epidemiology and population structure of Staphylococcus aureus in various population groups from a rural and semi urban area in Gabon, Central Africa

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• 作者：Ulysse Ateba Ngoa ; Frieder Schaumburg ; Ayola Akim Adegnika ; Katrin K?sters ; Tina M?ller ; Jose Francisco Fern ; es ; Abraham Alabi ; Saadou Issifou ; Karsten Becker ; Martin Peter Grobusch ; Peter Gottfried Kremsner ; Bertr ; Lell
• 关键词：Staphylococcus aureus ; MRSA ; Rural population ; Gabon ; Africa ; Genotyping
• 刊名：Acta Tropica
• 出版年：2012
• 出版时间：October, 2012
• 年：2012
• 卷：124
• 期：1
• 页码：42-47
• 全文大小：307 K

文摘

Little data is available on the epidemiology of Staphylococcus aureus in Africa. In the present study we aim at characterizing the population structure of S. aureus in healthy subjects from a rural and a semi-urban area in Lambar¨¦n¨¦, Gabon as well as in hospital staff and inpatients. In total, 500 subjects were screened for S. aureus colonization of the nares, axillae and inguinal region. Overall, 146 (29 % ) were positive. We found 46 different spa types. The most frequent spa types were t084 (35 % ) and the agr II was the most prevalent subtype of the accessory gene regulator (56 % , n = 82). Five isolates (3 % ) were methicillin resistant S. aureus (MRSA).

Carriage rates of S. aureus in Gabon are comparable to developed countries. MRSA is for the first time described and could pose a significant health threat in this region with limited access to microbiological laboratory facilities and to adequate antimicrobial agents.