The Chemotactic Cytokine Interleukin-8—A Cyst Fluid Marker for Malignant Epithelial Ovarian Cancer?

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• 作者：Ivarsson ; Karin ; Runesson ; Eva ; Sundfeldt ; Karin ; Haeger ; Magnus ; Hedin ; Lars ; Janson ; Per Olof ; et. al.
• 刊名：Gynecologic Oncology
• 出版年：1998
• 出版时间：December, 1998
• 年：1998
• 卷：71
• 期：3
• 页码：420-423
• 全文大小：73.8 K

文摘

Due to the difficulties in separating malignant and benign ovarian cysts by transvaginal ultrasound and other techniques, there is a need for biochemical markers in serum or cyst fluids. In the present study we have evaluated the levels of the chemokine interleukin-8 (IL-8) in ovarian cysts. IL-8 is known to be expressed in the normal ovary and to influence proliferation and angiogenesis of several nonovarian types of tumors. Cyst fluids from benign (n