Short synthesis of functionalized pentalongin derivatives using pyridinium ylid chemistry

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• 作者：Pieter Claes ; Jan Jacobs ; Sven Claessens ; Norbert De Kimpe
• 关键词：Pyranonaphthoquinones ; Pentalongin ; Pyridinium ylids
• 刊名：Tetrahedron
• 出版年：2010
• 出版时间：28 August 2010
• 年：2010
• 卷：66
• 期：35
• 页码：7088-7096
• 全文大小：652 K

文摘

3-Substituted pentalongin derivatives possessing an acetal function at C-1 were synthesized by cyclization of acylmethylnaphthoquinones. The latter naphthoquinones were prepared starting from 2-dioxolanylnaphthoquinone by means of both a stoichiometric and a catalytic method deploying various pyridinium ylids.