- 作者：Song E. Kim ; Won Sup Kim ; Byung Gon Kim ; Dongil Chung ; Jaeseung Jeong ; Jae Sung Lee ; Woo Suk Tae ; Seung Bong Hong ; Hyang Woon Lee
- 关键词：Visual evoked potential (VEP) ; Intracranial electrode ; Cortical localization ; Evoked neural oscillations ; Functional mapping
- 刊名：Clinical Neurophysiology
- 出版年：2013
- 出版时间：November, 2013
- 年：2013
- 卷：124
- 期：11
- 页码：2248-2256
- 全文大小：2604 K
Objective
To investigate spatiotemporal characteristics and functional correlates of evoked oscillations (EOs) at different frequency bands in human visual cortex.Methods
Flash visual evoked potentials (FVEPs) were recorded from 11 epilepsy patients with intracranial electrodes placed over the occipital and adjacent cortices. Spatiotemporal characteristics of spectral powers and correlation with various visual responses elicited by electrical cortical stimulations were analyzed in the same electrodes.
Results
High ¦Ã (60-150 Hz) EOs were first recorded in the cuneus and lingual gyri around the calcarine sulcus. Low ¦Ã (30-60 Hz) EOs appeared also in the mesial occipital cortex slightly later and lasted longer than high ¦Ã EGOs. In contrast, lower frequency (LF) <30 Hz EOs were recorded more diffusely from occipital surfaces with delayed onset and longer duration. High ¦Ã EOs were predominantly associated with simple form visual responses, whereas low ¦Ã and LF EOs were with intermediate form and LF EOs with complex form responses.
Conclusions
FVEP spectral power analysis directly recorded from human visual cortex showed distinct spatiotemporal distributions in high and low ¦Ã, or LF bands that have different functional correlates.
Significance
Phase-locked EOs in these frequency bands may have special neuroanatomical and functional organization during early visual processing.