Case-control study of DSWI over 3 year period in a contemporary cardiac surgery service, including a period of increased incidence.
Corroborates the role of red blood transfusions as a risk factor for DSWI, with an interaction with preoperative anemia.
Novel finding of chronic infections (defined as HIV, HBV, HCV, or bacterial infection ≥ 4 weeks, on antibiotics at surgery) as a risk factor for DSWI.
Antibiotic prophylaxis chosen did not cover organisms found in 77% of DSWIs.