Longitudinal treatment patterns among US patients with atherosclerotic cardiovascular disease or familial hypercholesterolemia initiating lipid-lowering pharmacotherapy

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• 作者：James P. Burke ; PhD^a ; ^{James.Burke@optum.com} ; Ross J. Simpson Jr. ; MD ; PhD^b ; Carly J. Paoli ; PharmD ; MPH^c ; Jeffrey T. McPheeters ; BA^a ; Shravanthi R. Gandra ; PhD ; MBA^c
• 关键词：Familial hypercholesterolemia ; High-dose statin ; High risk ; Treatment patterns ; Treatment discontinuation ; Treatment switching
• 刊名：Journal of Clinical Lipidology
• 出版年：2016
• 出版时间：November-December 2016
• 年：2016
• 卷：10
• 期：6
• 页码：1470-1480.e3
• 全文大小：525 K
• 卷排序：10

文摘

Treatment patterns in patients with elevated cardiovascular risk were examined. Most patients initiated on moderate-dose statins. After treatment initiation, statin dose uptitration was infrequent. Discontinuation was the most common pattern yet the majority reinitiated therapy.