Inverse birth cohort effects in ovarian cancer: Increasing risk in BRCA1/2 mutation carriers and decreasing risk in the general population
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- 作者：Janet R. Vosa ; j.r.vos01@umcg.nl" class="auth_mail" title="E-mail the corresponding author ; Marian J. Mouritsb ; Natalia Teixeiraa ; Liesbeth Jansenc ; Jan C. Oosterwijkd ; Geertruida H. de Bocka
- 关键词：Ovarian cancer ; BRCA1 gene ; BRCA2 gene ; Risk assessment ; Birth cohort
- 刊名：Gynecologic Oncology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：140
- 期：2
- 页码：289-294
- 全文大小：438 K
文摘
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In the general population ovarian cancer risk decreases with birth cohort.
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160">In BRCA carriers ovarian cancer risk increases with birth cohort.
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The reason for the opposite trends in carriers and general population is unknown.