An α-1 chain of type I collagen Sp1-binding site polymorphism in women suffering from stress urinary incontinence

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• 作者：Paweł ; Skorupski ; Jarosł ; aw Kró ; l ; Julia Starę ; ga ; Aneta Adamiak ; Katarzyna Jankiewicz ; Tomasz Rechberger
• 关键词：COLIA1 gene ; Sp1 polymorphism ; Stress urinary incontinence
• 刊名：American Journal of Obstetrics and Gynecology
• 出版年：2006
• 出版时间：February 2006
• 年：2006
• 卷：194
• 期：2
• 页码：346-350
• 全文大小：200 K

文摘

The embryogenesis and management of congenital urogenital anomalies that are associated with ureteric ectopia and the persistence of Gartner's duct are discussed. Ureteric ectopia with Gartner's duct cyst is caused by the failure of separation of the ureteric bud from the mesonephric duct, which leads to persistence of Gartner's duct, frequently with cystic dilation. Abnormal development of the ureter subsequently causes maldevelopment or absence of the ipsilateral kidney. The diagnosis and treatment of 2 adult women with congenital urethrovaginal fistula that was associated with unilateral single ectopic ureter, renal agenesis, and Gartner's duct anomaly are presented. Surgical repair of the urethrovaginal fistulae and removal of the Gartner's duct and cyst was performed transvaginally.