Impact of phosphatidylcholine liposomes on the compositional changes of VLDL during lipoprotein lipase (LPL)-mediated lipolysis
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- 作者：Agnieszka Ćwiklińska ; acwik@gumed.edu.pl" class="auth_mail" title="E-mail the corresponding author ; Anna Gliwińska ; Zuzanna Senderowska1 ; Barbara Kortas-Stempak ; Agnieszka Kuchta ; Kamil Dąbkowski ; Maciej Jankowski
- 关键词：Apo ; apolipoprotein ; CE ; cholesteryl ester ; FC ; free cholesterol ; HDL ; high density lipoprotein(s) ; HTG ; hipertriglyceridemia ; LpE ; lipoproteins containing apoE ; LPL ; lipoprotein lipase ; PC ; phosphatidylcholine ; PC-L ; phosphatidylcholine lipososomes ; PL ; phospholipids ; SUV ; small unilamellar liposomes ; TAG ; triacylglycerol(s) ; TC ; total cholesterol ; VLDL ; very low density lipoprotein(s)
- 刊名：Chemistry and Physics of Lipids
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：195
- 期：Complete
- 页码：63-70
- 全文大小：1070 K
文摘
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Phosphatidylcholine liposomes promote the release of surface material components from VLDL during LPL-mediated lipolysis.
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Reaction of VLDL with liposomes results in a decrease in VLDL apoCs/apoE and core/surface lipid weight ratios.
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Compositional changes in VLDL under the influence of liposomes are accompanied by an increase in VLDL lipolysis efficiency.
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New HDL-sized apoE-containing particles are generated during reaction between VLDL and liposomes.