Relations of circulating GDF-15, soluble ST2, and troponin-I concentrations with vascular function in the community: The Framingham Heart Study
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- 作者：Charlotte Anderssona ; ca@heart.dk" class="auth_mail" title="E-mail the corresponding author ; Danielle Enserrob ; Lisa Sullivanb ; Thomas J. Wanga ; c ; James L. Januzzi Jr.d ; Emelia J. Benjamina ; e ; f ; Joseph A. Vitag ; &dagger ; ; Naomi M. Hamburgg ; Martin G. Larsona ; Gary F. Mitchellh ; Ramachandran S. Vasana ; e ; f
- 关键词：Vascular stiffness ; Endothelial function ; Biomarkers ; ST2 ; GDF-15 ; Troponin I ; General population
- 刊名：Atherosclerosis
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：248
- 期：Complete
- 页码：245-251
- 全文大小：907 K
文摘
GDF-15, sST2, and hs-TnI are associated with incident cardiovascular disease (CVD), yet the underlying mechanisms are not fully understood.
We showed that GDF-15, sST2, and hs-TnI are related to several measures indicative of subclinical vascular dysfunction.
These findings may contribute to the associations between circulating GDF-15, sST2, and hs-TnI and incident CVD.