- 作者：Nicholas G.H. Mohtadi ; M.D. ; M.Sc. ; F.R.C.S.C.a ; mohtadi@ucalgary.ca ; Damian R. Griffin ; B.M. ; B.Ch. ; M.A. ; M.Phil. ; F.R.C.S. (Tr&Orth)b ; M. Elizabeth Pedersen ; M.D. ; F.R.C.S.C.c ; Denise Chan ; M.B.T. ; M.Sc.a ; Marc R. Safran ; M.D.d ; Nicholas Parsons ; Ph.D.b ; Jon K. Sekiya ; M.D.e ; Bryan T. Kelly ; M.D.f ; Jason R. Werle ; M.D. ; F.R.C.S.C.g ; Michael Leunig ; M.D.h ; Joseph C. McCarthy ; M.D.i ; Hal D. Martin ; D.O.j ; J.W. Thomas Byrd ; M.D.k ; Marc J. Philippon ; M.D.l ; RobRoy L. Martin ; Ph.D. ; P.T. ; C.S.C.S.m ; Carlos A. Guanche ; M.D.n ; John C. Clohisy ; M.D.o ; Thomas G. Sampson ; M.D.p ; Mininder S. Kocher ; M.D. ; M.P.H.q ; Christopher M. Larson ; M.D.r ; Multicenter Arthroscopy of the Hip Outcomes Research Network (MAHORN)
- 刊名：Arthroscopy: The Journal of Arthroscopic & Related Surgery
- 出版年：2012
- 出版时间：May, 2012
- 年：2012
- 卷：28
- 期：5
- 页码：595-610.e1
- 全文大小：1565 K
Purpose
The purpose of this study was to develop a self-administered evaluative tool to measure health-related quality of life in young, active patients with hip disorders.Methods
This outcome measure was developed for active patients (aged 18 to 60 years, Tegner activity level ¡Ý4) presenting with a variety of symptomatic hip conditions. This multicenter study recruited patients from international hip arthroscopy and arthroplasty surgeon practices. The outcome was created using a process of item generation (51 patients), item reduction (150 patients), and pretesting (31 patients). The questionnaire was tested for test-retest reliability (123 patients); face, content, and construct validity (51 patients); and responsiveness over a 6-month period in post-arthroscopy patients (27 patients).
Results
Initially, 146 items were identified. This number was reduced to 60 through item reduction, and the items were categorized into 4 domains: (1) symptoms and functional limitations; (2) sports and recreational physical activities; (3) job-related concerns; and (4) social, emotional, and lifestyle concerns. The items were then formatted using a visual analog scale. Test-retest reliability showed Pearson correlations greater than 0.80 for 33 of the 60 questions. The intraclass correlation statistic was 0.78, and the Cronbach ¦Á was .99. Face validity and content validity were ensured during development, and construct validity was shown with a correlation of 0.81 to the Non-Arthritic Hip Score. Responsiveness was shown with a paired t test (P ¡Ü .01), effect size of 2.0, standardized response mean of 1.7, responsiveness ratio of 6.7, and minimal clinically important difference of 6 points.
Conclusions
We have developed a new quality-of-life patient-reported outcome measure, the 33-item International Hip Outcome Tool (iHOT-33). This questionnaire uses a visual analog scale response format designed for computer self-administration by young, active patients with hip pathology. Its development has followed the most rigorous methodology involving a very large number of patients. The iHOT-33 has been shown to be reliable; shows face, content, and construct validity; and is highly responsive to clinical change. In our opinion the iHOT-33 can be used as a primary outcome measure for prospective patient evaluation and randomized clinical trials.