Atomic-level description of protein-lipid interactions using an accelerated membrane model
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- 作者：Javier L. Baylona ; b ; baylonc2@illinois.edu" class="auth_mail" title="E-mail the corresponding author ; Josh V. Vermaasa ; b ; vermaas2@illinois.edu" class="auth_mail" title="E-mail the corresponding author ; Melanie P. Mullera ; b ; c ; mmulle23@illinois.edu" class="auth_mail" title="E-mail the corresponding author ; Mark J. Arcarioa ; b ; c ; marcar2@illinois.edu" class="auth_mail" title="E-mail the corresponding author ; Taras V. Pogorelovb ; d ; e ; f ; pogorelo@illinois.edu" class="auth_mail" title="E-mail the corresponding author ; Emad Tajkhorshida ; b ; c ; g ; emad@life.illinois.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Membrane ; Peripheral proteins ; Molecular dynamics ; Lipids
- 刊名：Biochimica et Biophysica Acta (BBA)-Biomembranes
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：1858
- 期：7
- 页码：1573-1583
- 全文大小：2328 K
文摘
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The HMMM model is designed to enhance lipid dynamics in atomistic MD simulations.
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HMMM facilitates studying protein–lipid interactions to complement experiments.
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Recent applications of the HMMM model to study peripheral proteins are described.
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Challenges, limitations, and future directions of the HMMM model are discussed.