Fabrication and characterization of carboxymethyl cellulose novel microparticles for bone tissue engineering
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- 作者：Bipin Gaihrea ; Ambalangodage C. Jayasuriyaa ; b ; a.jayasuriya@utoledo.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Microparticles ; Carboxymethyl cellulose ; Zirconium ; Surface roughness ; Pre-osteoblasts
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 December 2016
- 年：2016
- 卷：69
- 期：Complete
- 页码：733-743
- 全文大小：2851 K
文摘
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Zirconium ions crosslinked carboxymethyl cellulose microparticles were fabricated.
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The microparticles were further stabilized by complexation with chitosan.
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The uniform distribution of zirconium promoted surface roughness.
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The microparticles were not cytotoxic and zirconium promoted osteoblast attachment.
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Sustained release of encapsulated drug was obtained from the microparticles.