Glycome complexity of human seminal plasma high molecular mass components: Evaluation of the contribution of acid-soluble glycoproteins/mucins and extracellular vesicles
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- 作者：Bojana Milutinovic ; bojana@inep.co.rs" class="auth_mail" title="E-mail the corresponding author ; Ninoslav Mitic ninoslavm@inep.co.rs" class="auth_mail" title="E-mail the corresponding author ; Jelena Roncevic jelena_ron@yahoo.com" class="auth_mail" title="E-mail the corresponding author ; Sanja Goc sanjagoc@inep.co.rs" class="auth_mail" title="E-mail the corresponding author ; Miroslava Jankovic miraj@inep.co.rs" class="auth_mail" title="E-mail the corresponding author
- 关键词：Seminal plasma ; Glycome ; Mucins ; Extracellular vesicles
- 刊名：Archives of Biochemistry and Biophysics
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：609
- 期：Complete
- 页码：20-30
- 全文大小：1927 K
文摘
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Seminal plasma glycans are selectively placed on its soluble and particulate fraction.
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Siaα2,6Gal and N-glycans are concentrated on extracellular vesicles (EVs).
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Siaα2,3Gal and short O-glycans are concentrated on mucins.
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Endogenous lectins DC-SIGN and Siglec-9 preferentially bound to EVs.